Lessons of the month 1: A case of rhombencephalitis as a rare complication of acute COVID-19 infection

Clin Med (Lond). 2020 May 15;20(3):293-294. doi: 10.7861/clinmed.2020-0182.


A 40-year-old man developed acute brainstem dysfunction 3 days after hospital admission with symptoms of the novel SARS-CoV-2 infection (COVID-19). Magnetic resonance imaging showed changes in keeping with inflammation of the brainstem and the upper cervical cord, leading to a diagnosis of rhombencephalitis. No other cause explained the patient's abnormal neurological findings. He was managed conservatively with rapid spontaneous improvement in some of his neurological signs and was discharged home with continued neurology follow up.

Keywords: COVID-19; MRI; brainstem encephalitis; hepatitis; rhombencephalitis.