Application of green tea extracts epigallocatechin-3-gallate in dental materials: Recent progress and perspectives

J Biomed Mater Res A. 2020 Dec;108(12):2395-2408. doi: 10.1002/jbm.a.36991. Epub 2020 Jul 9.

Abstract

Because of excellent biocompatibility, antioxidant activity, and anti-caries ability, epigallocatechin-3-gallate (EGCG) has been widely studied in the treatment of oral diseases, such as periodontal disease, oral cancer, and dental caries. To reach the site of the lesion or achieve sustained release, play the role of anti-caries, anti-inflammatory, or to maintain or improve the physical properties of the modified material,EGCG need to be cross-linked or embedded with dental adhesives, barrier membranes, bone replacement materials, tissue regeneration materials, and antimicrobial anti-caries materials to better prevent or treat oral diseases. This article reviews the applications of EGCG in oral materials, involving various areas of the oral cavity, reveals their excellent potential, and sees shortcomings in these research to promote the better development of EGCG applications in oral materials such as oral repair materials, bone tissue engineering materials and antibacterial and anti-caries materials.

Keywords: EGCG; dental materials; green tea.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Bacterial Agents* / chemistry
  • Anti-Bacterial Agents* / therapeutic use
  • Antioxidants* / chemistry
  • Antioxidants* / therapeutic use
  • Cariostatic Agents* / chemistry
  • Cariostatic Agents* / therapeutic use
  • Catechin / analogs & derivatives*
  • Catechin / chemistry
  • Catechin / therapeutic use
  • Dental Caries / drug therapy*
  • Humans
  • Periodontal Diseases / drug therapy*
  • Plant Extracts* / chemistry
  • Plant Extracts* / therapeutic use
  • Tea / chemistry*

Substances

  • Anti-Bacterial Agents
  • Antioxidants
  • Cariostatic Agents
  • Plant Extracts
  • Tea
  • Catechin
  • epigallocatechin gallate