Toxocara: Seroprevalence in Mexico

Adv Parasitol. 2020:109:341-355. doi: 10.1016/bs.apar.2020.01.012. Epub 2020 Feb 5.

Abstract

In Mexico, toxocariasis, like some other parasitosis in humans, is not a disease of conventional surveillance or immediate notification. Seroprevalence studies are scarce, six dealing with paediatric populations and eight dealing with adults; the reports were only from four states in Mexico. There were 1596 children, and the seroprevalence was 13.8%. In the case of adults, there were 1827 subjects, and seroprevalence was 4.7%. There is a significant positive association between seroprevalence and the paediatric population P<0.0001 (OR, 3.285; 95% CI, 2.541-4.279). It is advisable to perform competitive ELISAs and add another diagnostic test, such as Western blot or the detection of circulating antigens to reduce diagnostic uncertainty. This neglected parasitosis can be confused with retinoblastoma. Therefore, there is a risk of ocular enucleation. It is necessary to sensitise the authorities of the Ministry of Health and decision-makers, to provide economic support for epidemiological surveillance of this zoonotic parasite.

Keywords: Helminth transmitted by the soil; Paratenic hosts; Secretions-excretions; Seroprevalence; Toxocara; Toxocariasis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adult
  • Animals
  • Child
  • Dogs / psychology
  • Environment
  • Humans
  • Mexico / epidemiology
  • Seroepidemiologic Studies
  • Toxocara
  • Toxocariasis / epidemiology*