Visible-Light-Mediated Manganese-Catalyzed Allylation Reactions of Unactivated Alkyl Iodides

Xiaochen Wang; Jianyang Dong; Yongqiang Li; Yuxiu Liu; Qingmin Wang

doi:10.1021/acs.joc.0c00861

Visible-Light-Mediated Manganese-Catalyzed Allylation Reactions of Unactivated Alkyl Iodides

J Org Chem. 2020 Jun 5;85(11):7459-7467. doi: 10.1021/acs.joc.0c00861. Epub 2020 May 18.

Authors

Xiaochen Wang¹, Jianyang Dong¹, Yongqiang Li¹, Yuxiu Liu¹, Qingmin Wang^{1

2}

Affiliations

¹ State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin 300071, People's Republic of China.
² Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin 300071, People's Republic of China.

PMID: 32383380
DOI: 10.1021/acs.joc.0c00861

Abstract

Herein, we report a protocol for visible-light-mediated allylation reactions between unactivated alkyl iodides and allyl sulfones under mild conditions with catalysis by inexpensive and readily available Mn₂(CO)₁₀. This protocol is compatible with a wide array of sensitive functional groups and has a broad substrate scope with regard to both alkyl iodides and allyl sulfones.