Periodontitis and rheumatoid arthritis: An update 2012-2017

Periodontol 2000. 2020 Jun;83(1):189-212. doi: 10.1111/prd.12300.


Rheumatoid arthritis and chronic periodontitis are both chronic inflammatory diseases characterized by an exacerbated inflammatory reaction that leads to destruction of bone and other connective tissue. Owing to these similarities, the relationship between these two diseases has been investigated for over two decades. In the 2013 proceedings from a workshop jointly held by the European Federation of Periodontology and American Academy of Periodontology in 2012 it was concluded that there was at least minimal evidence of an association between periodontitis and rheumatoid arthritis. In this review, we consider publications in the field over the past 5 years and determine whether the evidence for this relationship has increased.

Publication types

  • Review

MeSH terms

  • Arthritis, Rheumatoid*
  • Bone and Bones
  • Chronic Periodontitis*
  • Humans
  • Inflammation