Utility of Photodynamic Therapy in Dentistry: Current Concepts

Dent J (Basel). 2020 May 7;8(2):43. doi: 10.3390/dj8020043.


The significant growth in scientific and technological advancements within the field of dentistry has resulted in a wide range of novel treatment modalities for dentists to use. Photodynamic therapy (PDT) is an emerging, non-invasive treatment method, involving photosensitizers, light of a specific wavelength and the generation of singlet oxygen and reactive oxygen species (ROS) to eliminate unwanted eukaryotic cells (e.g., malignancies in the oral cavity) or pathogenic microorganisms. The aim of this review article is to summarize the history, general concepts, advantages and disadvantages of PDT and to provide examples for current indications of PDT in various subspecialties of dentistry (oral and maxillofacial surgery, oral medicine, endodontics, preventive dentistry, periodontology and implantology), in addition to presenting some images from our own experiences about the clinical success with PDT.

Keywords: aminolevulinic acid; caries; endodontics; implantology; oral medicine; periodontology; photodynamic therapy; photosensitizer; reactive oxygen species.

Publication types

  • Review