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Review
. 2020 Apr;8(7):429.
doi: 10.21037/atm.2020.03.60.

Chinese Expert Brief Consensus on Newborn Screening of Inherited Metabolic Disorders During the Novel Coronavirus Infection Epidemic

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Free PMC article
Review

Chinese Expert Brief Consensus on Newborn Screening of Inherited Metabolic Disorders During the Novel Coronavirus Infection Epidemic

Shan Liu et al. Ann Transl Med. .
Free PMC article

Abstract

Novel coronavirus (2019-nCov) infection (COVID-19) rapidly spread across China and 25 countries in the worldwide, which infected not only adults but also children, even neonates. Each year, about 15 million newborns are delivered in China. Newborn screening (NBS) helps effectively prevent some mental retardation, premature death, and adverse outcomes in the early stage of baby, which could detect some inherited metabolic disorders (IMDs). During this COVID-19 epidemic, how to balance the risk of infected 2019-nCov and the risk of disability and teratogenesis of IMDs. Expert members of NBS extra quality assessment in National Clinical Center of Laboratory (NCCL) give a brief consensus for NBS of IMDs in the COVID-2019 epidemic, hoping that the brief consensus could be reference for NBS of IMDs in the other epidemic areas or periods all over the world.

Keywords: Novel coronavirus (2019-nCov); inherited metabolic disorders (IMDs); newborn screening (NBS).

Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/atm.2020.03.60). The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
The flow chart for newborn screening of IMDs during the COVID-19 period. The figure shows the flow chart for newborn screening of IMDs. And the difference during COVID-19 is marked in red. NBS, newborn screening; IMDs, inherited metabolic disorders; DBS, dried bloodspots; COVID, novel coronavirus infection disease; Lab, laboratory.

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