Salvage Bacteriophage Therapy for a Chronic MRSA Prosthetic Joint Infection

Antibiotics (Basel). 2020 May 9;9(5):241. doi: 10.3390/antibiotics9050241.


This is a case of a 72 year old male with a chronic methicillin-resistant Staphylococcus aureus prosthetic joint infection. After the third intravenous dose of bacteriophage therapy, an unusual, reversible transaminitis prompted stoppage of bacteriophage therapy. Nevertheless, treatment was successful and the patient's severe chronic infection was eradicated.

Keywords: bacteriophage therapy; biofilm; medication induced hepatitis; methicillin resistance Staphylococcus aureus; prosthetic joint infection.

Publication types

  • Case Reports