Cardiac operation under cardiopulmonary bypass during pregnancy

J Cardiothorac Surg. 2020 May 13;15(1):92. doi: 10.1186/s13019-020-01136-9.


Background: Certain pregnant women suffer from cardiac pathology,and a few of them need cardiac operations under cardiopulmonary bypass during pregnancy. Feto-neonatal and maternal outcomes have not been sufficiently described.

Methods: We conducted a retrospective review of 22 cases of women undergoing cardiac operations under cardiopulmonary bypass during pregnancy in our hospital from Jan.2014 to Mar.2019.

Results: All 22 patients were alive after treatment. The types of cardiac disorders included congenital heart defects, rheumatic heart disease,infective endocarditis,aortic dissection, obstruction and/or thrombosis of a prosthetic valve. Only one case was a twin pregnancy,and the other 21 cases were singletons. Four fetuses died in the utero after surgery. Three patients chose termination of the pregnancy after the cardiac operations: one fetus was detected abnormity of the brain and the other two patients abandoned pregnancy. Fourteen fetuses were alive and born without any abnormity. Two fetuses suffered from neonatal intracranial hemorrhage and died after birth.

Conclusions: Cardiac operation under cardiopulmonary bypass during pregnancy is a challenge for physicians in multidisciplinary teams. Strictly evaluating the indication is vital. On the other hand, some patients can benefit from this management.

Keywords: Cardiac operation; Cardiopulmonary bypass; Outcome; Pregnancy.

MeSH terms

  • Adult
  • Cardiac Surgical Procedures / methods*
  • Cardiac Surgical Procedures / mortality
  • Cardiopulmonary Bypass* / mortality
  • Female
  • Fetal Mortality
  • Humans
  • Infant
  • Infant Mortality
  • Infant, Newborn
  • Pregnancy
  • Pregnancy Complications, Cardiovascular / surgery*
  • Retrospective Studies
  • Treatment Outcome
  • Young Adult