Onco-Cardiology: Consensus Paper of the German Cardiac Society, the German Society for Pediatric Cardiology and Congenital Heart Defects and the German Society for Hematology and Medical Oncology

Clin Res Cardiol. 2020 Oct;109(10):1197-1222. doi: 10.1007/s00392-020-01636-7. Epub 2020 May 13.


The acute and long-lasting side effects of modern multimodal tumour therapy significantly impair quality of life and survival of patients afflicted with malignancies. The key components of this therapy include radiotherapy, conventional chemotherapy, immunotherapy and targeted therapies. In addition to established tumour therapy strategies, up to 30 new therapies are approved each year with only incompletely characterised side effects. This consensus paper discusses the risk factors that contribute to the development of a potentially adverse reaction to tumour therapy and, in addition, defines specific side effect profiles for different treatment groups. The focus is on novel therapeutics and recommendations for the surveillance and treatment of specific patient groups.

Keywords: Cancer therapy; Cardio-oncology; Cardiotoxicity; Chemotherapy; Survivorship programs.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents / administration & dosage
  • Antineoplastic Agents / adverse effects
  • Cardiovascular Diseases / etiology*
  • Cardiovascular Diseases / physiopathology
  • Combined Modality Therapy
  • Germany
  • Humans
  • Immunotherapy / adverse effects
  • Immunotherapy / methods
  • Neoplasms / therapy*
  • Quality of Life
  • Radiotherapy / adverse effects
  • Radiotherapy / methods
  • Risk Factors


  • Antineoplastic Agents