Characteristics and Outcomes of Coronavirus Disease Patients under Nonsurge Conditions, Northern California, USA, March-April 2020

Emerg Infect Dis. 2020 Aug;26(8):1679-1685. doi: 10.3201/eid2608.201776. Epub 2020 May 14.

Abstract

Limited data are available on the clinical presentation and outcomes of coronavirus disease (COVID-19) patients in the United States hospitalized under normal-caseload or nonsurge conditions. We retrospectively studied 72 consecutive adult patients hospitalized with COVID-19 in 2 hospitals in the San Francisco Bay area, California, USA, during March 13-April 11, 2020. The death rate for all hospitalized COVID-19 patients was 8.3%, and median length of hospitalization was 7.5 days. Of the 21 (29% of total) intensive care unit patients, 3 (14.3% died); median length of intensive care unit stay was 12 days. Of the 72 patients, 43 (59.7%) had underlying cardiovascular disease and 19 (26.4%) had underlying pulmonary disease. In this study, death rates were lower than those reported from regions of the United States experiencing a high volume of COVID-19 patients.

Keywords: COVID-19; California; Coronavirus diseases; ICU; SARS-CoV-2; United States; coronavirus disease; hospitalization; mortality; outcomes; pneumonia; respiratory diseases; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.

Publication types

  • Observational Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adenosine Monophosphate / analogs & derivatives
  • Adenosine Monophosphate / therapeutic use
  • Aged
  • Aged, 80 and over
  • Alanine / analogs & derivatives
  • Alanine / therapeutic use
  • Asthma / epidemiology
  • Asthma / physiopathology
  • Azithromycin / therapeutic use
  • Betacoronavirus / pathogenicity*
  • COVID-19
  • COVID-19 Testing
  • California / epidemiology
  • Clinical Laboratory Techniques / methods
  • Comorbidity
  • Coronavirus Infections / diagnosis
  • Coronavirus Infections / drug therapy
  • Coronavirus Infections / epidemiology*
  • Coronavirus Infections / mortality
  • Diabetes Mellitus / epidemiology*
  • Diabetes Mellitus / physiopathology
  • Female
  • Humans
  • Hyperlipidemias / epidemiology*
  • Hyperlipidemias / physiopathology
  • Hypertension / epidemiology*
  • Hypertension / physiopathology
  • Intensive Care Units
  • Length of Stay
  • Male
  • Pandemics*
  • Pneumonia, Viral / diagnosis
  • Pneumonia, Viral / drug therapy
  • Pneumonia, Viral / epidemiology*
  • Pneumonia, Viral / mortality
  • Pulmonary Disease, Chronic Obstructive / epidemiology
  • Pulmonary Disease, Chronic Obstructive / physiopathology
  • Retrospective Studies
  • Reverse Transcriptase Polymerase Chain Reaction
  • SARS-CoV-2
  • Severity of Illness Index
  • Survival Analysis
  • Tomography, X-Ray Computed

Substances

  • remdesivir
  • Adenosine Monophosphate
  • Azithromycin
  • Alanine