A More Granular View of Neutrophils in Malaria

Trends Parasitol. 2020 Jun;36(6):501-503. doi: 10.1016/j.pt.2020.03.003. Epub 2020 Apr 6.


Neutrophils are abundant innate immune cells with crucial roles in immunity and vascular inflammation. Recent evidence indicates that neutrophils have a dual role in malaria, contributing to both pathogenesis and control of Plasmodium. We discuss emerging mechanisms behind these opposing functions and identify key outstanding questions.

Keywords: innate immunity; malaria; neutrophils.