Rheologic properties of soft tissue fillers and implications for clinical use

J Cosmet Dermatol. 2021 Jan;20(1):28-34. doi: 10.1111/jocd.13487. Epub 2020 Aug 7.

Abstract

Background: The use of injectable soft-tissue fillers has become an essential tool in esthetic rejuvenation. Rheology, the study of flow of matter, helps to understand the function of these products.

Aims: The purpose of this article is to review the rheologic properties of soft-tissue fillers currently available in the United States and to evaluate how these properties relate to clinical performance.

Methods: This article explains basic rheologic terms and describes how rheologic properties of specific soft-tissue fillers affect filler performance.

Results: The currently available soft-tissue fillers have unique rheologic and physicochemical properties that influence performance and cosmetic outcome. These properties determine that filler product is most appropriate based on degree of soft-tissue defect and anatomic location.

Conclusion: It is imperative for physicians to have an in-depth understanding of the rheologic properties of soft-tissue fillers in order to appropriately select and utilize these products for the desired cosmetic outcome.

Keywords: cosmetic dermatology; dermal filler; elasticity; hyaluronic acid; intradermal injections; rheology.

Publication types

  • Review

MeSH terms

  • Cosmetic Techniques*
  • Dermal Fillers* / adverse effects
  • Humans
  • Hyaluronic Acid
  • Rejuvenation
  • Rheology
  • Skin Aging*

Substances

  • Dermal Fillers
  • Hyaluronic Acid