Blackfly fever and dermatitis caused by Simulium kiritshenkoi: a human case report in Iran

BMC Infect Dis. 2020 May 15;20(1):348. doi: 10.1186/s12879-020-05070-y.


Background: Besides the considerable role of blackflies to the transmission of many disease agents, these flies considered as annoying biting pests of wildlife, livestock, poultry, and humans. There are few literature reports of blackfly fever following Simulium spp. This study describes a case of blackfly fever and dermatitis following blackflies numerous bites in Iran.

Case presentation: The present report describes a 25-year-old man that was attacked by numerous flies while fishing and camping near Namrood river in Firuzkuh County, Tehran Province, Iran. Pruritic dermatitis with marked edema appeared mainly on the hands and legs and subsequently, the patient's condition worsened with swollen lymph nodes, joints aching, and 40 °C fever. The patient's clinical signs and symptoms were alleviated by injection of intramuscular Dexamethasone Phosphate (DEXADIC®) 8 mg/2 ml after 24 h.

Conclusions: This study reported a human case with blackfly fever and dermatitis following numerous bites of Simulium kiritshenkoi, for the first time in Iran.

Keywords: Blackfly fever; Case report; Dermatitis; Iran; Simulium.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Animals
  • Dermatitis / drug therapy
  • Dermatitis / etiology*
  • Dexamethasone / analogs & derivatives
  • Dexamethasone / therapeutic use
  • Edema / drug therapy
  • Edema / etiology
  • Female
  • Fever / etiology*
  • Hand
  • Humans
  • Insect Bites and Stings / complications*
  • Insect Bites and Stings / drug therapy
  • Iran
  • Leg
  • Male
  • Simuliidae* / anatomy & histology
  • Simuliidae* / physiology


  • dexamethasone 21-phosphate
  • Dexamethasone