Metronomic Oral Vinorelbine and Lung Cancer Therapy During the COVID 19 Pandemic: A Single-Center Experience

Lung Cancer. 2020 Jul;145:83-84. doi: 10.1016/j.lungcan.2020.05.001. Epub 2020 May 6.


COVID 19 pandemic is a worldwide health emergency. Every single Hospital and Department was forced to radically modify clinical practice decreasing or stopping daily activities. Oncological patients had to carry on treatments in order to prevent disease progression and improve their quality of life. However, many health workers may be a potential source of infection if not tested with swabs but this diagnostic procedure was not suitable universally in Italy. Aiming to reduce hospitalization of our patients with advanced lung cancer, vinorelbine in its metronomic formulation is one of the best strategy. Here, we report the experience with oral vinorelbine in a few patients of our Oncology Department.

Keywords: Lung cancer; Oral; Vinorelbine.

MeSH terms

  • Administration, Oral
  • Betacoronavirus / pathogenicity
  • Coronavirus Infections / complications
  • Coronavirus Infections / drug therapy*
  • Coronavirus Infections / pathology
  • Coronavirus Infections / virology
  • Humans
  • Lung Neoplasms / complications
  • Lung Neoplasms / drug therapy*
  • Lung Neoplasms / pathology
  • Lung Neoplasms / virology
  • Pandemics*
  • Pneumonia, Viral / complications
  • Pneumonia, Viral / drug therapy*
  • Pneumonia, Viral / pathology
  • Pneumonia, Viral / virology
  • Quality of Life
  • Vinorelbine / therapeutic use*


  • Vinorelbine

Supplementary concepts

  • COVID-19
  • severe acute respiratory syndrome coronavirus 2