COVID-19: An Update About the Discovery Clinical Trial

Pharmaceuticals (Basel). 2020 May 14;13(5):98. doi: 10.3390/ph13050098.

Abstract

Finding efficacious and safe treatments for COVID-19 emerges as a crucial need in order to control the spread of the pandemic. Whereas plasma therapy attracts much interest, the European project Discovery focuses on the potentialities of small molecules like remdesivir, the combination of lopinavir/ritonavir, hydroxychloroquine, and chloroquine. Results recently published on the clinical evaluation of those drugs are compiled in this brief report, although complete data are still impatiently awaited.

Keywords: COVID-19; SARS-CoV-2; chloroquine; hydroxychloroquine; lopinavir/ritonavir; plasma; remdesivir.