Computer-based quantification of an atraumatic sinus augmentation technique using CBCT

J Biol Regul Homeost Agents. 2019 Nov-Dec;33(6 Suppl. 2):31-39. DENTAL SUPPLEMENT.


Our group recently developed an innovative maxillary sinus augmentation technique without the need of sinus membrane elevation, termed as "IPG" DET protocol. This technique utilizes autologous platelet concentrates (including platelet rich plasma (PRP), platelet rich fibrin (PRF), growth factors (GFs) and CD34+ stem cells), together with bone grafting materials positioned through intentionally perforated Schneider's membrane for flapless implant placement. This study aimed at evaluating the performance of "IPG" DET protocol in terms of new bone formation and implant stability at 8 months post-op. This prospective study consisted of forty-eight patients with a mean age of 52.8 years. A total of eighty-five implants were placed with "IPG" DET protocol in combination with autologous platelet concentrates. CBCT (cone beam computed tomography) was performed at two different time points: pre-operatively and at 8 months post-op. CBCT images were then compared by an intensity-based image algorithm to assess the newly formed bone in terms of gray scale values. Additionally, implant stability quotient (ISQ) was used to estimate implant osseointegration and success rate. The average new bone formation was 5.9 ± 0.9 mm2 per implant. All implants successfully osseointegrated, and ISQ ranged 62.3-71.7. According to the results of this study, "IPG" DET protocol in combination with autologous platelet concentrates is a successful technique for implant-supported rehabilitation of the edentulous posterior maxilla without the need of sinus floor elevation.

Keywords: autologous platelet concentrates; computer-based quantification; cone beam computed tomography; implant stability quotient; sinus floor elevation.

MeSH terms

  • Bone Transplantation
  • Dental Implants*
  • Humans
  • Maxillary Sinus / diagnostic imaging
  • Maxillary Sinus / surgery
  • Middle Aged
  • Platelet-Rich Fibrin*
  • Prospective Studies
  • Sinus Floor Augmentation*
  • Spiral Cone-Beam Computed Tomography*


  • Dental Implants