Integrative Analysis of the Genes Induced by the Intestine Microbiota of Infant Born to Term and Breastfed

Bioinform Biol Insights. 2020 Apr 29:14:1177932220906168. doi: 10.1177/1177932220906168. eCollection 2020.

Abstract

Nowadays, the integration of biological data is a major challenge for bioinformatics. Many studies have examined gene expression in the epithelial tissue in the intestines of infants born to term and breastfed, generating a large amount of data. The integration of these data is important to understand the biological processes involved during bacterial colonization of the newborns intestine, particularly through breast milk. This work aims to exploit the bioinformatics approaches, to provide a new representation and interpretation of the interactions between differentially expressed genes in the host intestine induced by the microbiota.

Keywords: Gene expression; breastfed; intestinal microbiota; network; newborn.