[Experimental research on the antitumor effectiveness of Bac. intermedius RNAse]

Eksp Onkol. 1988;10(6):54-7.
[Article in Russian]

Abstract

Identity of the mechanism of antitumour effectiveness of Bac. intermedius and pancreatic RNase and the enzyme independence of the catalytical activity are shown. Differential sensitivity of the implanted tumours of animals to RNase of Bac. intermedius is established.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Antineoplastic Agents*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Bacillus / enzymology*
  • Dose-Response Relationship, Drug
  • Drug Screening Assays, Antitumor
  • Drug Synergism
  • Mice
  • Neoplasm Transplantation
  • Neoplasms, Experimental / drug therapy
  • Ribonuclease, Pancreatic / therapeutic use
  • Ribonucleases / therapeutic use*
  • Vincristine / administration & dosage

Substances

  • Antineoplastic Agents
  • Vincristine
  • Ribonucleases
  • Ribonuclease, Pancreatic