Invasive Group B Streptococcus Infections in Adults, England, 2015-2016

Emerg Infect Dis. 2020 Jun;26(6):1174-1181. doi: 10.3201/eid2606.191141.


During 2015-2016, a total of 3,156 episodes of invasive group B Streptococcus (iGBS) infection in adults (>15 years of age) were recorded in England, corresponding to an annual incidence of 3.48/100,000 population. iGBS incidence was highest in older patients and women of childbearing age. The 493 pregnancy-related iGBS episodes correspond to a rate of 1.34/10,000 live births. In adults up to 60-69 years of age and in pregnant women, iGBS incidence increased with higher levels of socioeconomic deprivation. Hospital admissions associated with iGBS were predominantly emergency admissions (73% [2,260/3,099]); only 7% of nonpregnancy iGBS diagnoses were made >48 hours after admission. Underlying conditions were highly prevalent in nonpregnant adult case-patients, including cardiovascular (57%), lung (43%), and kidney (45%) disease and diabetes (40%). Post-iGBS episode 30-day and 12-month all-cause mortality rates in nonpregnant adults were 12% and 24%, respectively. No pregnancy-related iGBS deaths were identified.

Keywords: England; Streptococcus agalactiae; adult; bacteria; epidemiology; group B Streptococcus; invasive infection; streptococci.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • England / epidemiology
  • Female
  • Hospitalization
  • Humans
  • Incidence
  • Pregnancy
  • Streptococcal Infections* / epidemiology
  • Streptococcus agalactiae*