Private variants in PRKN are associated with late-onset Parkinson's disease

Affiliations

• ¹ Department of Neurology, Universitätsklinikum Schleswig-Holstein, Christian-Albrechts-University, Kiel, Germany; Department of Neurology, Hannover Medical School, Hannover, Germany.
• ² Department of Neurology, UKSH, Christian-Albrechts-University, Kiel, Germany; Institute of Health Informatics, University College London, London, UK.
• ³ Institute of Medical Informatics and Statistics, Kiel University, University Hospital Schleswig-Holstein, 24105, Kiel, Germany.
• ⁴ Institute of Epidemiology, University of Kiel, Germany.
• ⁵ Institute of Clinical Molecular Biology, Kiel University, University Hospital Schleswig-Holstein, Campus Kiel, Rosalind-Franklin-Straße 12, 24105, Kiel, Germany.
• ⁶ Institute of Neurogenetics, University of Lübeck, Lübeck, Germany.
• ⁷ Institute of Epidemiology II, German Research Center for Environmental Health, Helmholtz Zentrum München, Neuherberg, Germany; Research Unit of Molecular Epidemiology, German Research Center for Environmental Health, Helmholtz Zentrum München, Neuherberg, Germany; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.
• ⁸ Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany; Chair of Genetic Epidemiology, Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-University, Munich, Germany.
• ⁹ Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, 85764, Germany; Department of Medicine I, Ludwig-Maximilians-Universität, Munich, 80539, Germany; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, 80636, Germany.
• ¹⁰ Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany.
• ¹¹ Institute of Neurogenomics, Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.
• ¹² Institute of Neurogenomics, Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany; Institut für Humangenetik, Klinikum rechts der Isar, Fakultät für Medizin, Technische Universität München, Ismaninger Straße 22, 81675, München, Germany; Munich Cluster for Systems Neurology (SyNergy), München, Germany.
• ¹³ Paracelsus-Elena-Klinik Kassel, Kassel, Germany; Department of Neurology, University Medical Center Göttingen, Göttingen, Germany.
• ¹⁴ Department Neurosurgery, University Medical Center, Goettingen, Germany; Paracelsus-Elena Hospital, Kassel, Germany.
• ¹⁵ Department of Neurology, UKSH, Christian-Albrechts-University, Kiel, Germany.
• ¹⁶ Institute of Neurogenetics, University of Lübeck, Lübeck, Germany; Department of Psychiatry and Psychotherapy, University of Lübeck, Germany.
• ¹⁷ Technical University of Munich, School of Medicine, Department of Neurology, Munich, Germany; German Center for Neurodegenerative Diseases, Munich, Germany; Department of Neurology, Hannover Medical School, Hannover, Germany.
• ¹⁸ Hertie Institute for Clinical Brain Research and German Center for Neurodegenerative Diseases, University Clinic Tuebingen, Tuebingen, Germany.
• ¹⁹ Department of Neurology, UKSH, Christian-Albrechts-University, Kiel, Germany. Electronic address: Gregor.Kuhlenbaeumer@uksh.de.