Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Oct 20;173(8):672-675.
doi: 10.7326/M20-2428. Epub 2020 May 26.

Loss of Smell and Taste in 2013 European Patients With Mild to Moderate COVID-19

Jerome R Lechien  1 , Carlos M Chiesa-Estomba  2 , Stephane Hans  3 , Maria Rosaria Barillari  4 , Lionel Jouffe  5 , Sven Saussez  6
Affiliations

Loss of Smell and Taste in 2013 European Patients With Mild to Moderate COVID-19

Jerome R Lechien et al. Ann Intern Med. .
No abstract available

PubMed Disclaimer

Figures

Figure.
Figure.
Flow chart of the study. * The diagnostic tests of ambulatory and hospitalized patients were centralized in hospital laboratories, allowing identification of patients with positive results. † For hospitalized patients, physicians entered information directly on an online questionnaire; home-managed (quarantined) patients completed the questionnaire at home. ‡ Among the patients with total loss of smell, those who came from Hainaut, Belgium, were contacted to be included in a second study to objectively assess the olfactory disorder. The following exclusion criteria were considered: history of nasal surgery, history of head or neck trauma, history of chronic rhinosinusitis or polyposis, degenerative neurologic disease, and history of chronic loss of smell before the epidemic. Patients who did not respond to the questionnaire were excluded (n = 7).
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Lechien JR, Chiesa-Estomba CM, Place S, et al; COVID-19 Task Force of YO-IFOS. Clinical and epidemiological characteristics of 1,420 European patients with mild-to-moderate coronavirus disease 2019. J Intern Med. 2020. [PMID: 32352202] doi:10.1111/joim.13089. - PMC - PubMed
    1. Rodriguez-Morales AJ, Cardona-Ospina JA, Gutiérrez-Ocampo E, et al; Latin American Network of Coronavirus Disease 2019-COVID-19 Research (LANCOVID-19). Clinical, laboratory and imaging features of COVID-19: a systematic review and meta-analysis. Travel Med Infect Dis. 2020;34:101623. [PMID: 32179124] doi:10.1016/j.tmaid.2020.101623. - PMC - PubMed
    1. Rawal S, Hoffman HJ, Bainbridge KE, et al. Prevalence and risk factors of self-reported smell and taste alterations: results from the 2011-2012 US National Health and Nutrition Examination Survey (NHANES). Chem Senses. 2016;41:69-76. [PMID: 26487703] doi:10.1093/chemse/bjv057. - PMC - PubMed
    1. Hummel T, Kobal G, Gudziol H, et al. Normative data for the “Sniffin' Sticks” including tests of odor identification, odor discrimination, and olfactory thresholds: an upgrade based on a group of more than 3,000 subjects. Eur Arch Otorhinolaryngol. 2007;264:237-43. [PMID: 17021776] - PubMed
    1. Brann DH, Tsukahara T, Weinreb C, et al. Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia. Preprint. Posted online 9 April 2020. bioRxiv 009084. doi:10.1101/2020.03.25.009084. - PMC - PubMed