Beyond Stiffness: Collagen Signaling in Pancreatic Cancer and Pancreas Regeneration

Am J Pathol. 2020 Aug;190(8):1622-1624. doi: 10.1016/j.ajpath.2020.05.005. Epub 2020 May 22.


This commentary highlights the article by Ruggeri et al that reports the importance of discoidin domain receptor 1 in tissue homeostasis in pancreatic injury and pancreatic ductal adenocarcinoma pathogenesis.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Carcinoma, Pancreatic Ductal*
  • Collagen
  • Discoidin Domain Receptor 1
  • Homeostasis
  • Humans
  • Pancreatic Neoplasms*
  • Regeneration


  • Collagen
  • DDR1 protein, human
  • Discoidin Domain Receptor 1