Vitamin D can prevent COVID-19 infection-induced multiple organ damage

Naunyn Schmiedebergs Arch Pharmacol. 2020 Jul;393(7):1157-1160. doi: 10.1007/s00210-020-01911-4. Epub 2020 May 25.

Abstract

Vitamin D is an immunomodulator hormone with an anti-inflammatory and antimicrobial effect with a high safety profile. A lot of COVID-19 infected patients develop acute respiratory distress syndrome (ARDS), which may lead to multiple organ damage. These symptoms are associated with a cytokine storm syndrome. The aim of this letter is to note the 5 crucial points that vitamin D could have protective and therapeutic effects against COVID-19. For that reason, COVID-19 infection-induced multiple organ damage might be prevented by vitamin D.

Keywords: Covid-19; Cytokine storm; Multiple organ damage; Vitamin D.

Publication types

  • Letter

MeSH terms

  • Anti-Inflammatory Agents / administration & dosage*
  • Anti-Inflammatory Agents / pharmacology
  • Coronavirus Infections / complications*
  • Coronavirus Infections / drug therapy
  • Coronavirus Infections / virology
  • Cytokine Release Syndrome / prevention & control
  • Cytokine Release Syndrome / virology
  • Humans
  • Multiple Organ Failure / prevention & control
  • Multiple Organ Failure / virology
  • Pandemics
  • Pneumonia, Viral / complications*
  • Pneumonia, Viral / drug therapy
  • Pneumonia, Viral / virology
  • Respiratory Distress Syndrome, Adult / prevention & control
  • Respiratory Distress Syndrome, Adult / virology
  • Vitamin D / administration & dosage*
  • Vitamin D / pharmacology

Substances

  • Anti-Inflammatory Agents
  • Vitamin D

Supplementary concepts

  • COVID-19
  • COVID-19 drug treatment