Scar sarcoidosis following rituximab therapy

Dermatol Ther. 2020 Nov;33(6):e13693. doi: 10.1111/dth.13693. Epub 2020 Jul 3.


Drug-induced sarcoidosis has been rarely described but it constitutes a potential side effect of immunomodulatory medications. We report a case of rituximab-induced scar sarcoidosis and review similar published cases. Although there is evidence of B-cell dysregulation in the pathogenesis of sarcoidosis, the use of rituximab for this disease needs to be carefully evaluated based on reports of worsening and de novo development of sarcoidosis after rituximab therapy.

Keywords: rituximab; sarcoidosis; scar.

Publication types

  • Case Reports

MeSH terms

  • B-Lymphocytes
  • Cicatrix* / chemically induced
  • Cicatrix* / diagnosis
  • Cicatrix* / pathology
  • Humans
  • Rituximab* / adverse effects
  • Sarcoidosis* / chemically induced
  • Sarcoidosis* / diagnosis


  • Rituximab