Polyamine block of MthK potassium channels

J Gen Physiol. 2020 Jul 6;152(7):e202012614. doi: 10.1085/jgp.202012614.


Polyamines can modulate membrane excitability by blocking ion flux through ion channels. Suma et al. determined the location of the binding site for polyamines inside a model potassium channel pore.

Publication types

  • Comment

MeSH terms

  • Ion Channel Gating
  • Polyamines
  • Potassium Channels* / metabolism
  • Potassium Channels, Calcium-Activated* / metabolism


  • Polyamines
  • Potassium Channels
  • Potassium Channels, Calcium-Activated