Characterization of the novel HLA-DQA1*01:49 allele by sequencing-based typing

HLA. 2020 Aug;96(2):233-234. doi: 10.1111/tan.13949. Epub 2020 Jun 13.

Authors

Marine Cargou^{1

2}, Marco Andreani³, Franco Locatelli^{3

4}, Laura Blouin¹, Jonathan Visentin^{1

2}

Affiliations

¹ CHU de Bordeaux, Laboratoire d'Immunologie et Immunogénétique, Hôpital Pellegrin, Place Amélie Raba Léon, Bordeaux, France.
² Université de Bordeaux, UMR CNRS 5164 Immunoconcept, Bordeaux, France.
³ Laboratorio d'Immunogenetica dei Trapianti, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy.
⁴ Department of Pediatrics, Sapienza, University of Rome, Rome, Italy.

PMID: 32462804
DOI: 10.1111/tan.13949

Abstract

HLA-DQA1*01:49 differs from HLA-DQA1*01:01:01:06 by one nucleotide substitution in codon 9 in exon 2.

Keywords: HLA-DQA1*01:49; human leukocyte antigen; novel allele; sequencing-based typing.

© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

MeSH terms

Alleles*
Exons / genetics
HLA-DQ alpha-Chains / genetics
Humans
Sequence Analysis, DNA

Substances

HLA-DQ alpha-Chains
HLA-DQA1 antigen