Polymerase Acidic Subunit I38T Mutant Influenza A(H3N2) Virus Isolated from a Pediatric Patient without Prior Baloxavir Marboxil Treatment in Mie Prefecture (November 2018)

Jpn J Infect Dis. 2020 Sep 24;73(5):383-385. doi: 10.7883/yoken.JJID.2019.210. Epub 2020 May 29.

Authors

Takuya Yano¹, Hitoshi Ochiai², Shigehiro Akachi¹, Yoshiharu Matsumura¹

Affiliations

¹ Mie Prefecture Health and Environment Research Institute, Japan.
² Ochiai Pediatric Clinics, Japan.

PMID: 32475868
DOI: 10.7883/yoken.JJID.2019.210

No abstract available

Keywords: I38T mutant influenza; baloxavir marboxil; polymerase acidic.

MeSH terms

Adolescent
Antiviral Agents / therapeutic use*
Child
Child, Preschool
Dibenzothiepins / therapeutic use*
Drug Resistance, Viral*
Female
Humans
Infant
Influenza A Virus, H3N2 Subtype / genetics*
Influenza A Virus, H3N2 Subtype / isolation & purification
Influenza, Human / drug therapy*
Influenza, Human / virology
Japan
Male
Microbial Sensitivity Tests
Morpholines / therapeutic use*
Mutation
Pyridones / therapeutic use*
RNA-Dependent RNA Polymerase / genetics
Triazines / therapeutic use*
Viral Proteins / genetics

Substances

Antiviral Agents
Dibenzothiepins
Morpholines
PA protein, influenza viruses
Pyridones
Triazines
Viral Proteins
baloxavir
RNA-Dependent RNA Polymerase