The effect of fish oil supplementation on the promotion and preservation of lean body mass, strength, and recovery from physiological stress in young, healthy adults: a systematic review

Nutr Rev. 2020 Dec 1;78(12):1001-1014. doi: 10.1093/nutrit/nuaa034.

Abstract

Context: Military personnel are subjected to physiologically stressful environments during combat and its associated training. Evidence suggests that fish oil-derived n-3 polyunsaturated fatty acids (FO n-3 PUFAs) may affect military personnel's performance by promoting or preserving lean body mass, strength, and power, while enhancing recovery from training-associated muscle damage.

Objective: Following PRISMA guidelines, this systematic review assessed the evidence for FO n-3 PUFA supplementation across various military-relevant outcomes related to physical performance in healthy adult populations.

Data sources: The PubMed, Embase, and the CINAHL databases were searched along with references lists of selected articles and reviews.

Data extraction: Eighteen trials were assessed for bias, and descriptive data were extracted.

Data analysis: Of the 18 studies included, 12 trials favored FO n-3 PUFA supplementation in ≥ 1 of the performance outcomes.

Conclusion: Overall, FO n-3 PUFA supplementation likely preserves strength and very likely enhances recovery from physiological stress in young, healthy adults. However, FO n-3 PUFAs' role in promoting or preserving lean body mass or promoting strength is unclear and warrants additional investigation.

Systematic review registration: PROSPERO registration no. CRD42020152786.

Keywords: military; n-3 polyunsaturated fatty acids; skeletal muscle health.

Publication types

  • Systematic Review

MeSH terms

  • Adult
  • Anabolic Agents / pharmacology
  • Body Fluid Compartments / metabolism*
  • Dietary Supplements*
  • Fatty Acids, Omega-3 / pharmacology
  • Fatty Acids, Unsaturated / pharmacology
  • Female
  • Fish Oils / pharmacology*
  • Humans
  • Male
  • Military Personnel
  • Muscle Strength / drug effects*
  • Muscle, Skeletal / drug effects*
  • Physical Conditioning, Human
  • Physical Functional Performance*
  • Stress, Physiological*
  • Young Adult

Substances

  • Anabolic Agents
  • Fatty Acids, Omega-3
  • Fatty Acids, Unsaturated
  • Fish Oils