Effects of Exercise on Proactive Interference in Memory: Potential Neuroplasticity and Neurochemical Mechanisms

Psychopharmacology (Berl). 2020 Jul;237(7):1917-1929. doi: 10.1007/s00213-020-05554-4. Epub 2020 Jun 2.


Proactive interference occurs when consolidated memory traces inhibit new learning. This kind of interference decreases the efficiency of new learning and also causes memory errors. Exercise has been shown to facilitate some types of cognitive function; however, whether exercise reduces proactive interference to enhance learning efficiency is not well understood. Thus, this review discusses the effects of exercise on proactive memory interference and explores potential mechanisms, such as neurogenesis and neurochemical changes, mediating any effect.

Keywords: Exercise; Neurogenesis; Neurotransmitter systems; Proactive interference.

Publication types

  • Review