Possible long-term endocrine-metabolic complications in COVID-19: lesson from the SARS model

Endocrine. 2020 Jun;68(3):467-470. doi: 10.1007/s12020-020-02349-7. Epub 2020 Jun 2.

Abstract

The outbreak of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is centralizing the interest of the scientific world. In the next months, long-term consequences on the endocrine system may arise following COVID-19. In this article, we hypothesized the effects of SARS-CoV-2 taking into account what learned from the severe acute respiratory syndrome coronavirus (SARS-CoV) that caused SARS in 2003.

Keywords: Adrenal Glands; COVID-19; Diabetes; Obesity; Pituitary gland; SARS.

Publication types

  • Editorial

MeSH terms

  • Angiotensin-Converting Enzyme 2
  • Betacoronavirus*
  • COVID-19
  • Coronavirus Infections / complications*
  • Coronavirus Infections / virology
  • Endocrine Glands / virology*
  • Endocrine System Diseases / metabolism*
  • Endocrine System Diseases / virology*
  • Female
  • Humans
  • Male
  • Pandemics
  • Peptidyl-Dipeptidase A
  • Pneumonia, Viral / complications*
  • Pneumonia, Viral / virology
  • SARS-CoV-2
  • Severe Acute Respiratory Syndrome / complications*
  • Severe acute respiratory syndrome-related coronavirus

Substances

  • Peptidyl-Dipeptidase A
  • ACE2 protein, human
  • Angiotensin-Converting Enzyme 2