Periodontitis and Cardiovascular Diseases. Consensus Report

Glob Heart. 2020 Feb 3;15(1):1. doi: 10.5334/gh.400.


Background: In Europe cardiovascular disease (CVD) is responsible for 3.9 million deaths (45% of deaths), being ischaemic heart disease, stroke, hypertension (leading to heart failure) the major cause of these CVD related deaths. Periodontitis is also a chronic non-communicable disease (NCD) with a high prevalence, being severe periodontitis, affecting 11.2% of the world's population, the sixth most common human disease.

Material and methods: There is now a significant body of evidence to support independent associations between severe periodontitis and several NCDs, in particular CVD. In 2012 a joint workshop was held between the European Federation of Periodontology (EFP) and the American Academy of Periodontology to review the literature relating periodontitis and systemic diseases, including CVD. In the last five years important new scientific information has emerged providing important emerging evidence to support these associations.

Results and conclusions: The present review reports the proceedings of the workshop jointly organised by the EFP and the World Heart Federation (WHF), which has updated the existing epidemiological evidence for significant associations between periodontitis and CVD, the mechanistic links and the impact of periodontal therapy on cardiovascular and surrogate outcomes. This review has also focused on the potential risk and complications of periodontal therapy in patients on anti thrombotic therapy and has made recommendations for dentists, physicians and for patients visiting both the dental and medical practices.

Keywords: Periodontitis; antitrombotic therapy; atherosclerosis; bacteremia; cardiovascular diseases; chronic inflammation; periodontal therapy.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Cardiovascular Diseases / epidemiology
  • Cardiovascular Diseases / etiology*
  • Consensus*
  • Europe / epidemiology
  • Humans
  • Incidence
  • Periodontitis / complications*

Grants and funding

This workshop was funded through an unrestricted grant from DENTAID SA to the European Federation of Periodontology to organize the EFP/EHF Workshop. All individual experts participating in the workshop have declared no conflict of interest with the results of the consensus workshop or the publication.