Beta-Lactamase Inhibitors

Excerpt

Beta-lactamase inhibitors are co-administered with beta-lactam antimicrobials to prevent antimicrobial resistance. They do this by inhibiting serine beta-lactamases, enzymes that inactivate the beta-lactam ring which are a common chemical structure to all beta-lactam antimicrobials. This activity outlines the different types of beta-lactamase inhibitors. It discusses the pharmacological properties of beta-lactamase inhibitors, their medical uses, administration methods, side effects, and other properties. It also highlights providers' critical role in correctly administering beta-lactamase inhibitors in combination with beta-lactam antimicrobials and counseling patients regarding medication adherence.