Foot ulceration is among the most common health issues, and its prevalence has increased recently. It is one of the major causes of amputations, particularly in patients with uncontrolled diabetes. The lifetime foot risk of developing a foot ulcer in patients with diabetes is more than 33%. Diabetic foot ulcer causes a lot of morbidities and accounts for approximately two-thirds of all United States non-traumatic amputations. Infections in these patients are thought to be limb-threatening conditions.
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