Detecting Warm Temperatures Is a Cool Kind of Thing

Neuron. 2020 Jun 3;106(5):712-714. doi: 10.1016/j.neuron.2020.05.009.

Abstract

In this issue of Neuron, Paricio-Montesinos et al. (2020) unveil the essential cellular elements for warm temperature detection in mice. Surprisingly, the silencing of spontaneously firing, unmyelinated, polymodal sensory afferents harboring cold-activated TRPM8 channels is the key neural mechanism.

Publication types

  • Comment

MeSH terms

  • Animals
  • Cold Temperature
  • Hot Temperature
  • Mice
  • Neurons
  • TRPM Cation Channels*
  • Temperature

Substances

  • TRPM Cation Channels