Treatment of Acute Venous Thromboembolism

Med Clin North Am. 2020 Jul;104(4):631-646. doi: 10.1016/j.mcna.2020.03.004.

Abstract

"Acute venous thromboembolism is a common disease seen by nearly all hospitalists. The advent of low molecular weight heparin (LMWH) several decades ago ushered in the era of early hospital discharge and home treatment. More recently, the direct oral anticoagulants (DOACs) have further simplified outpatient treatment and some offer treatment without parenteral therapy. Use of DOACs for cancer-associated venous thromboembolism is emerging and is a welcome evolution of care to spare oncologic patients the burden of daily LMWH injections."

Keywords: Anticoagulation; Deep vein thrombosis; Pulmonary embolism; Risk stratification; Thrombolytic.

Publication types

  • Review

MeSH terms

  • Administration, Oral
  • Anticoagulants / adverse effects
  • Anticoagulants / therapeutic use*
  • Hemorrhage / chemically induced
  • Heparin, Low-Molecular-Weight / therapeutic use
  • Humans
  • Neoplasms / complications
  • Pulmonary Embolism / therapy
  • Risk Assessment
  • Surgical Procedures, Operative
  • Venous Thromboembolism / etiology
  • Venous Thromboembolism / therapy*
  • Venous Thrombosis / etiology
  • Venous Thrombosis / therapy*
  • Vitamin K / antagonists & inhibitors

Substances

  • Anticoagulants
  • Heparin, Low-Molecular-Weight
  • Vitamin K