Occurrence and Timing of Subsequent SARS-CoV-2 RT-PCR Positivity Among Initially Negative Patients

Clin Infect Dis. 2020 Jun 7;ciaa722. doi: 10.1093/cid/ciaa722. Online ahead of print.

Abstract

Using data for 20,912 patients from two large academic health systems, we analyzed the frequency of SARS-CoV-2 RT-PCR test-discordance among individuals initially testing negative by nasopharyngeal swab who were retested on clinical grounds within 7 days. The frequency of subsequent positivity within this window was 3.5% and similar across institutions.

Keywords: COVID-19; SARS-CoV-2 RT-PCR; nasopharyngeal; test characteristics; testing.