Dataset of allele, genotype and haplotype frequencies of five polymorphisms CDKN2B-AS1 gene in Russian patients with primary open-angle glaucoma

Natalya Eliseeva; Irina Ponomarenko; Evgeny Reshetnikov; Alexey Polonikov; Irina Batlutskaya; Inna Aristova; Anna Elykova; Natalya Rudykh; Mikhail Churnosov

doi:10.1016/j.dib.2020.105722

Dataset of allele, genotype and haplotype frequencies of five polymorphisms CDKN2B-AS1 gene in Russian patients with primary open-angle glaucoma

Data Brief. 2020 May 18:31:105722. doi: 10.1016/j.dib.2020.105722. eCollection 2020 Aug.

Authors

Natalya Eliseeva¹, Irina Ponomarenko¹, Evgeny Reshetnikov¹, Alexey Polonikov², Irina Batlutskaya¹, Inna Aristova¹, Anna Elykova¹, Natalya Rudykh¹, Mikhail Churnosov¹

Affiliations

¹ Department of Medical Biological Disciplines, Belgorod State University, 308015 Belgorod, Russia.
² Department of Biology, Medical Genetics and Ecology, Kursk State Medical University, 305041 Kursk, Russia.

Abstract

Data on the allele, genotype and haplotype frequencies of the five single nucleotide polymorphisms (SNPs) such as rs1063192, rs7865618, rs2157719, rs944800 and rs4977756 of the CDKN2B-AS gene in Russian patients with primary open-angle glaucoma (POAG) are provided. These SNPs are found to be associated with the risk of POAG by genome-wide association studies (GWAS). The frequencies of alleles, genotypes and haplotypes of CDKN2B-AS gene were present separately for entire group of patients, females and males, and may be used as reference data of Russian population.

Keywords: CDKN2B-AS gene; Female; Male; Primary open-angle glaucoma; Single nucleotide polymorphism.