90Y-Radioembolization After Failed Portal Vein Embolization for Colorectal Liver Metastases: A Case Report

Cardiovasc Intervent Radiol. 2020 Aug;43(8):1232-1236. doi: 10.1007/s00270-020-02537-y. Epub 2020 Jun 8.

Abstract

The main limiting factor for liver resection is insufficient future liver remnant (FLR). Portal vein embolization (PVE) is a standard of care treatment to induce FLR hypertrophy, but it is not always efficient. Radioembolization (RE) has a potential to induce liver hypertrophy for PVE-refractory patients. However, this was reported only for the patients with hepatocellular carcinoma. We described two cases of lobar RE after PVE failure for the patients with colorectal liver metastases. This enabled to reach sufficient FLR, provide good local disease control and bridge the patients to extended hepatectomy.

Keywords: Ablation; Colorectal cancer; Liver metastases; Radioembolization.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Brachytherapy / methods*
  • Colorectal Neoplasms / pathology*
  • Embolization, Therapeutic / methods*
  • Humans
  • Liver Neoplasms / radiotherapy*
  • Liver Neoplasms / secondary*
  • Liver Neoplasms / therapy
  • Male
  • Middle Aged
  • Treatment Outcome
  • Yttrium Radioisotopes / administration & dosage*

Substances

  • Yttrium Radioisotopes