Cytoskeletal Repair: Microtubule Orthopaedics to the Rescue

Curr Biol. 2020 Jun 8;30(11):R646-R649. doi: 10.1016/j.cub.2020.04.049.


While the dynamics of microtubule ends are well characterized, the mechanism that repairs breaks in the lattice interior is poorly understood. A new in vitro study finds that the microtubule-associated protein CLASP repairs lattice damage by regulating GTP-tubulin incorporation into the break site.

Publication types

  • Comment

MeSH terms

  • Microtubule-Associated Proteins
  • Microtubules
  • Orthopedics*
  • Tubulin*


  • Microtubule-Associated Proteins
  • Tubulin