[Early intracerebral hemorrhage as an atypical presentation of herpes simplex-1 virus encephalitis]

Rev Peru Med Exp Salud Publica. 2020 Jan-Mar;37(1):155-159. doi: 10.17843/rpmesp.2020.371.4384. Epub 2020 Jun 8.
[Article in Spanish]

Abstract

Herpes simplex encephalitis is the most common cause of sporadic lethal encephalitis in the world. Intracerebral hemorrhage is an uncommon complication. The case of a 3-year-old preschooler who was admitted with acute encephalitis clinical picture is described. The patient presents findings of early in tracerebral hemorrhage in the occipital region and a positive cerebrospinal fluid study for herpes virus type 1, which is treated with acyclovir; however, it presents a torpid evolution, increased intracerebral hemorrhages and fatal outcome.

La encefalitis por herpes virus simple es la causa más común de encefalitis esporádica letal en el mundo. Una complicación poco usual es la hemorragia intracerebral. Se describe el caso de un preescolar de tres años que ingresa con cuadro clínico de encefalitis aguda, con hallazgos de hemorragia intracerebral temprana en región occipital y estudio en líquido cefalorraquídeo positivo para herpes virus tipo 1, que recibe tratamiento con aciclovir; sin embargo, cursa con evolución tórpida, incremento de hemorragias intracerebrales y desenlace fatal.

Publication types

  • Case Reports

MeSH terms

  • Cerebral Hemorrhage* / diagnosis
  • Cerebral Hemorrhage* / virology
  • Child, Preschool
  • Encephalitis, Herpes Simplex* / complications
  • Fatal Outcome
  • Humans