Multiple Limb Involvement in a Severe Case of Complex Regional Pain Syndrome Treated With Spinal Cord Stimulation: A Case Report

A A Pract. 2020 May;14(7):e01224. doi: 10.1213/XAA.0000000000001224.


Complex regional pain syndrome (CRPS) can be a debilitating, persistent, and treatment-resistant pain condition. This report presents a case of severe CRPS affecting multiple limbs, resistant to standard treatment modalities. Treatment with spinal cord stimulation (SCS) had an initial good effect. Nevertheless, the CRPS continued to progress, eventually affecting all 4 extremities. A lead fracture resulted in a rapidly developing recurrence of CRPS in the patient's arm, necessitating amputation. SCS may be an effective modality for treatment of severe CRPS. However, mechanical problems should always be considered when an SCS-implanted patient experiences rapid symptom progression or abrupt cessation of stimulation.

Publication types

  • Case Reports

MeSH terms

  • Complex Regional Pain Syndromes / therapy*
  • Extremities
  • Humans
  • Male
  • Middle Aged
  • Spinal Cord Stimulation*
  • Treatment Outcome