Comparison of Efficacy and Long-Term Survival of Laparoscopic Radical Nephrectomy With Partial Nephrectomy in the Treatment of Patients With Early Renal Cell Carcinoma Running Title: Laparoscopic Radical Nephrectomy

J BUON. Mar-Apr 2020;25(2):1155-1160.

Abstract

Purpose: To compare the efficacy and long-term survival of laparoscopic radical nephrectomy (LRN) with laparoscopic partial nephrectomy (LPN) in the treatment of patients with early renal cell carcinoma (RCC).

Methods: A retrospective analysis was performed on the medical records of 146 patients, aged 40-60 years, with T1bN0M0 RCC admitted to Chongqing Three Gorges Central Hospital. The patients were divided into a study group (n=62) treated with LPN and a control group (n=84) treated with LRN according to surgical methods. The renal function, one month after operation and surgery-related indicators and the incidence of postoperative complications were analyzed.

Results: One month after operation GFR was significantly higher in the study group than in the control group (p<0.05), which was lower than that before operation in the two groups (p<0.05).

Conclusion: The short- and long-term efficacy of LPN is similar to that of LRN in the treatment of T1bN0M0 RCC, but LPN better preserves the renal function, which has a potential value in reducing cardiovascular events.