A Gap Between Asthma Guidelines and Management for Adolescents and Young Adults

J Allergy Clin Immunol Pract. 2020 Oct;8(9):3056-3065.e2. doi: 10.1016/j.jaip.2020.05.034. Epub 2020 Jun 6.

Abstract

Background: For adolescents, asthma management can be challenging during the transition to adulthood, and changes in health care and pharmacological treatment may occur.

Objective: To investigate asthma-related health care consumption and pharmacological dispensation during the transition process.

Methods: In a Swedish birth cohort study, questionnaire and clinical data from the 16- and 24-year follow-ups were linked to national and regional registries for asthma-related health care consumption and dispensed medications during an 8-year period: 4 years before and after age 18 y, respectively.

Results: In the study population (n = 1808), 14% fulfilled the study definition of current asthma at the 16- and 24-year follow-up and 8% (n = 147) had persistent asthma. Among them, register data showed that in the 4-year period before their 18th birthday, 39% (58 of 147) had at least 1 consultation, similar to 37% (55 of 147) in the following 4-year period. The mean number of consultations before age 18 years was 1.6, compared with 1.0 after age 18 years (P = .02). At least 1 dispensation of any inhaled corticosteroid before age 18 years was found for 73% (107 of 147), compared with 50% (74 of 147) after age 18 years. The mean number of dispensed any inhaled corticosteroid was 3.1 before 18 years and 2.1 after 18 years (P < .01). Only 3% (5 of 147) had a regular dispensation of any inhaled corticosteroid once a year during the 8-year period.

Conclusions: Health care consultations were fewer than recommended in guidelines and decreased after the transition to adult health care. Almost no one had dispensed regular asthma medications during the 8-year period.

Keywords: Adolescents; Adult health care; Birth cohort; Guidelines; Level of care; Management; Pediatric and adult health care; Phenotypes; Severity; Young adults.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Inhalation
  • Adolescent
  • Adrenal Cortex Hormones / therapeutic use
  • Adult
  • Anti-Asthmatic Agents* / therapeutic use
  • Asthma* / drug therapy
  • Asthma* / epidemiology
  • Cohort Studies
  • Humans
  • Registries
  • Sweden / epidemiology
  • Young Adult

Substances

  • Adrenal Cortex Hormones
  • Anti-Asthmatic Agents