Recurrent High-grade Ovarian Immature Teratoma with Peritoneal Dissemination

J Pediatr Adolesc Gynecol. 2020 Oct;33(5):586-589. doi: 10.1016/j.jpag.2020.06.002. Epub 2020 Jun 11.

Abstract

Background: Peritoneal dissemination of ovarian immature teratoma in children is a rare entity and is associated with a poor prognosis. There are no guidelines on the optimal management of these patients with regard to surgery and systemic treatments.

Case: This is the case of a 16-year-old patient who experienced an early recurrence of immature teratoma with peritoneal dissemination after surgery and systemic chemotherapy failure, and was treated with an aggressive salvage cytoreductive surgery. She was still disease-free 6 months after her second surgery.

Summary and conclusion: Upfront aggressive surgical management with complete cytoreductive surgery is recommended when patients present with disease recurrence and peritoneal dissemination of ovarian immature teratoma. Such cases should be managed in centers with local expertise in the treatment of peritoneal surface malignancies.

Keywords: Carcinomatosis; Immature teratoma; Ovarian cancer; Pediatric oncology; Recurrence.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Cytoreduction Surgical Procedures / methods
  • Female
  • Humans
  • Neoplasm Recurrence, Local / diagnostic imaging
  • Neoplasm Recurrence, Local / pathology*
  • Neoplasm Recurrence, Local / surgery
  • Ovarian Neoplasms / diagnostic imaging
  • Ovarian Neoplasms / pathology*
  • Ovarian Neoplasms / surgery
  • Salvage Therapy / methods
  • Teratoma / diagnostic imaging
  • Teratoma / pathology*
  • Teratoma / surgery
  • Tomography, X-Ray Computed

Supplementary concepts

  • Teratoma, Ovarian