Accidental Overdose Deaths in Oklahoma, 2002-2017: Opioid and Methamphetamine Trends

J Anal Toxicol. 2020 Oct 12;44(7):672-678. doi: 10.1093/jat/bkaa068.

Abstract

To evaluate trends related to accidental overdose deaths in Oklahoma, with a focus on opioids and methamphetamine. All accidental drug overdose deaths in the state of Oklahoma from 2002 to 2017 were reviewed. Opioids were grouped into the following categories: all opioids, prescription opioids, synthetic opioids and heroin. Age-adjusted death rates for methamphetamine and each opioid category were calculated and analyzed. Accidental overdoses accounted for 9,936 deaths during the study period. Of these, opioids were seen in 62.9%, with prescription opioids comprising 53.8%, synthetic opioids 10.3% and heroin 2.8%. Synthetic opioids, despite a recent upward nationwide trend, showed a slight overall decrease (-6.8%) from 2009 to 2017. In contrast, methamphetamine showed a 402.2% increase from 2009 to 2017 and an overall increase of 1,526.7%. Methamphetamine was involved in the most overdoses (1,963), followed by oxycodone (1,724). Opioid-related deaths were most common among white individuals (90.3%) and showed a slight male predilection (56.9%). With the intent of assessing the opioid epidemic as it relates to accidental overdoses in Oklahoma, this study suggests that opioid-related overdoses have slowed in recent years amidst a sharp increase in methamphetamine deaths.

MeSH terms

  • Adult
  • Analgesics, Opioid / poisoning
  • Drug Overdose / mortality*
  • Female
  • Heroin / poisoning
  • Humans
  • Male
  • Methamphetamine / poisoning
  • Oklahoma / epidemiology
  • Opioid-Related Disorders / mortality*
  • Oxycodone / poisoning

Substances

  • Analgesics, Opioid
  • Methamphetamine
  • Heroin
  • Oxycodone