Rhodotorula dairenensis fungemia in a patient with cancer

Rev Iberoam Micol. 2020 Apr-Jun;37(2):63-64. doi: 10.1016/j.riam.2020.03.006. Epub 2020 Jun 13.

Abstract

Background: Rhodotorula species were traditionally considered non-virulent environmental microorganisms, but are nowadays considered important human pathogens, especially in immunocompromised individuals.

Case report: We present the case of a 73 year-old man with diarrhea, anorexia and fever. In the blood analyses, both aerobic blood culture bottles yielded the growth of Rhodotorula dairenensis. The MALDI-TOF MS score was inadequate to provide an identification, which was achieved by means of molecular techniques. Treatment with an echinocandin was started, but the patient died.

Conclusions: Basidiomycetous yeast genera such as Rhodotorula can cause invasive and severe infections, e.g., fungemia, especially in patients with central venous catheter or another indwelling device.

Keywords: Catéter venoso; Diagnóstico molecular; Fungemia; Molecular diagnosis; Rhodotorula dairenensis; Venous catheter.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / complications*
  • Adenocarcinoma / drug therapy
  • Adenocarcinoma / secondary
  • Adrenal Cortex Hormones / administration & dosage
  • Aged
  • Antineoplastic Agents / therapeutic use
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Caspofungin / therapeutic use
  • Cetuximab / administration & dosage
  • Cetuximab / adverse effects
  • Colonic Neoplasms / complications*
  • Colonic Neoplasms / drug therapy
  • Fatal Outcome
  • Fungemia / complications
  • Fungemia / drug therapy
  • Fungemia / microbiology*
  • Humans
  • Immunocompromised Host
  • Intestinal Obstruction / etiology
  • Irinotecan / administration & dosage
  • Irinotecan / adverse effects
  • Male
  • Peritoneal Neoplasms / complications
  • Rhodotorula / isolation & purification*

Substances

  • Adrenal Cortex Hormones
  • Antineoplastic Agents
  • Irinotecan
  • Caspofungin
  • Cetuximab

Supplementary concepts

  • Rhodotorula dairenensis