The Effect of Theracurmin on Cognitive Function in an Older Patient with Chemobrain

Clin Interv Aging. 2020 May 19:15:691-693. doi: 10.2147/CIA.S252229. eCollection 2020.


Chemobrain is one of the problems that may arise during or after treatment and there is currently no specific treatment for this condition. Our case was a 76-year-old female patient who presented to our clinic with complaints of forgetfulness that did not affect daily living activities for the last year. Breast cancer was diagnosed in 2013 and she has been receiving anastrozole treatment for 6 years after local mass excision surgery and radiotherapy. After a comprehensive geriatric evaluation, cognitive impairment due to systemic cancer therapy was detected and treatment was started with Theracurmin 90 mg twice a day therapy. After 3-months of Theracurmin therapy, she had no cognitive improvement during the follow-up. This case report demonstrated that Theracurmin treatment may be a new option for chemobrain.

Keywords: Theracurmin; cancer; chemobrain; cognitive impairment; elderly.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anastrozole* / administration & dosage
  • Anastrozole* / adverse effects
  • Antineoplastic Agents, Hormonal / administration & dosage
  • Antineoplastic Agents, Hormonal / adverse effects
  • Breast Neoplasms / pathology
  • Breast Neoplasms / therapy*
  • Cognition / drug effects*
  • Cognition Disorders* / diagnosis
  • Cognition Disorders* / drug therapy
  • Cognition Disorders* / etiology
  • Curcumin / administration & dosage*
  • Female
  • Geriatric Assessment / methods
  • Humans
  • Mastectomy, Segmental / methods
  • Nootropic Agents / administration & dosage
  • Radiotherapy* / adverse effects
  • Radiotherapy* / methods
  • Treatment Outcome


  • Antineoplastic Agents, Hormonal
  • Nootropic Agents
  • Anastrozole
  • Curcumin