Antibodies in the breast milk of a maternal woman with COVID-19

Yunzhu Dong; Xiangyang Chi; Huang Hai; Liangliang Sun; Mengyao Zhang; Wei-Fen Xie; Wei Chen

doi:10.1080/22221751.2020.1780952

Antibodies in the breast milk of a maternal woman with COVID-19

Emerg Microbes Infect. 2020 Dec;9(1):1467-1469. doi: 10.1080/22221751.2020.1780952.

Authors

Yunzhu Dong¹, Xiangyang Chi¹, Huang Hai², Liangliang Sun², Mengyao Zhang¹, Wei-Fen Xie², Wei Chen¹

Affiliations

¹ Beijing Institute of Biotechnology, Beijing, People's Republic of China.
² Changzheng Hospital, Second Military Medical University, Shanghai, People's Republic of China.

Abstract

A maternal woman was positive for SARS-CoV-2 tested in throat swabs but negative tested in other body fluids, and she had IgG and IgA detected in breast milk. Her infant negative for SARS-CoV-2 at birth had elevated IgG in serum but quickly decayed. These findings suggest that breastfeeding might have the potential benefit to the neonates.

Keywords: COVID-19; IgA; IgG; breastmilk; maternal woman.

Publication types

Case Reports
Letter

MeSH terms

Adult
Antibodies, Viral / analysis*
Antibodies, Viral / immunology
Betacoronavirus / immunology*
COVID-19
China
Coronavirus Infections / immunology*
Female
Humans
Immunoglobulin A / analysis
Immunoglobulin G / analysis
Infant, Newborn
Milk, Human / immunology*
Milk, Human / virology
Pandemics
Pneumonia, Viral / immunology*
Pregnancy
Pregnancy Complications, Infectious / immunology
Pregnancy Complications, Infectious / virology*
SARS-CoV-2

Substances

Antibodies, Viral
Immunoglobulin A
Immunoglobulin G

Grant support

This work is supported by grants of the National Key R&D Program of China (2020YFC0841400) and National Nature Science Foundation of China (81803429).