Overseeing Memory Circuits by NFIA: New Face In Astrocytes

Qingyun Li

doi:10.1016/j.neuron.2020.05.027

Overseeing Memory Circuits by NFIA: New Face In Astrocytes

Neuron. 2020 Jun 17;106(6):878-880. doi: 10.1016/j.neuron.2020.05.027.

Author

Qingyun Li¹

Affiliation

¹ Department of Neuroscience, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: qingyunli@wustl.edu.

PMID: 32553203
DOI: 10.1016/j.neuron.2020.05.027

Abstract

Astrocytes are heterogeneous controlling numerous aspects of brain function. In this issue of Neuron, Huang et al. (2020) uncover a novel role of NFIA, which regulates unique properties of adult hippocampal astrocytes via region-specific DNA binding, thereby modulating the plasticity of local circuits.

Publication types

Comment

MeSH terms

Astrocytes*
Hippocampus
Memory*
Neurons